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No pharmacokinetic information is available on selegiline or its metabolites in renally impaired subjects.

Selegiline is an enzyme blockerMAO inhibitorthat works by slowing the breakdown of certain natural substances in the brainneurotransmitters such as dopaminenorepinephrineand serotonin

No pharmacokinetic information is available on selegiline or Here,,,,,,,,,,,,, here, here, here, here, here, here, here, here, here, here, here. its metabolites in hepatically impaired subjects.

Some studies concluded in an increased risk of mortality in patients receiving selegiline and levodopa compared to those receiving levodopa onlyHoweverit is noteworthy that multiple methodological bias were identified in these studies and that a meta analysis and large cohort studies concluded that there was no significant difference in mortality in patients treated with selegiline to those treated with comparators or with the association selegiline/levodopa.

Eldeprylselegilineprevents Here,,,,,,,,,,,,, here, here, here, here, here, here, here, here, here, here, here. the breakdown of a chemical in your brain called dopamineLow levels of dopamine are associated with Parkinson’s disease.

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